P116 Serum PARC (CCL18) and exacerbation frequency in COPD
نویسندگان
چکیده
منابع مشابه
Exacerbation frequency and course of COPD
BACKGROUND Exacerbations affect morbidity in chronic obstructive pulmonary disease (COPD). We sought to evaluate the association between exacerbation frequency and spirometric and health status changes over time using data from a large, long-term trial. METHODS This retrospective analysis of data from the 4-year UPLIFT (Understanding Potential Long-term Impacts on Function with Tiotropium) tr...
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Introduction: COPD is a common preventable disease characterized by airflow limitation that is not completely reversible.Acute exacerbation is prominent and serious features of COPD. Acute Exacerbation of COPD leads to hospitalization and concomitant with morbidity and mortality .The ventricular dysfunction increases serum Brain Natriuretic Peptide(BNP) . This study was conducted to evaluate t...
متن کاملSERPINA1 11478G/A variant, serum a1-antitrypsin, exacerbation frequency and FEV1 decline in COPD
Background The a1-antitrypsin 11478G/A polymorphism may be associated with attenuated acute a1-antitrypsin responses. It was hypothesised that patients with chronic obstructive pulmonary disease (COPD) and this mutation have accelerated lung function
متن کاملSERPINA1 11478G→A variant, serum α1-antitrypsin, exacerbation frequency and FEV1 decline in COPD.
BACKGROUND The α(1)-antitrypsin 11478G→A polymorphism may be associated with attenuated acute α(1)-antitrypsin responses. It was hypothesised that patients with chronic obstructive pulmonary disease (COPD) and this mutation have accelerated lung function decline. OBJECTIVE To assess whether the 11478G→A polymorphism is associated with attenuated α(1)-antitrypsin responses at COPD exacerbation...
متن کاملCCL18/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis.
Hypersensitivity pneumonitis (HP) is a lung inflammatory disorder characterized by accumulation of T lymphocytes. However, the mechanisms implicated in this process remain undefined. We examined the expression of dendritic cell (DC)-derived CC chemokine 1 (CK1)/CCL18, a chemokine putatively involved in naive T cell recruitment, in lungs from 10 patients with HP, 9 patients with idiopathic pulmo...
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ژورنال
عنوان ژورنال: Thorax
سال: 2010
ISSN: 0040-6376
DOI: 10.1136/thx.2010.150987.17